Congress detail

Authors: Spetale, Flavio; E. Tapia; J. Murillo; F. Krsticevic; Ponce, Sergio; L. Angelone; Bulacio, Pilar.

Title: Proper integration of feature subsets boosts GO subcellular localization predictions.

Resumen: Abstract?Prediction of multiple subcellular localizationsin proteins brings relevant information for biological functiondiscovery. The use of computational methods based onknowledge can be a helpful starting point for guiding thecostly experimental validation. In this work, we present amultilabel classifier framework to perform Gene Ontology -Cellular Component prediction focused on the improvementof two design aspects: i) the protein sequence characterization,regarding biological knowledge with experimental evidence,and ii) the error evaluation by considering a noise modelinherent in real prediction frameworks.Our proposal is validated against sets of well-known proteinsequences of four model organisms D. rerio, A. thaliana, S.cerevisiae and D. melanogaster.

Meeting type: Congreso.

Type of job: Artículo Completo.

Production: Proper integration of feature subsets boosts GO subcellular localization predictions.

Scientific meeting: XXI CONGRESO ARGENTINO DE BIOINGENIERI, X JORNADA DE INGENIERÍA CLÍNICA,A - SABI 2017.

Meeting place: Córdoba.

Organizing Institution: Facultad de Ciencias Exactas, Físicas y Naturales en conjunto con la Facultad de Ciencias Médicas, de la Universidad Nacional de Córdoba.

It's published?: Yes

Publication place: Córdoba

Meeting month: 10

Year: 2017.

Link: here